UnTouchableChristina Applegate on living with MS, and the night a room stood up
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Christina Applegate shared this about their own health, publicly. Everything below is written in our own words, from the sources listed at the end.
Speaking to Robin Roberts at length for the first time about her multiple sclerosis diagnosis, Christina Applegate did not soften it. She said she lives kind of in hell, and that she is not out much, so even doing the interview was difficult for her system.
She talked about presenting at the Emmys, and the standing ovation that met her. She said she more or less blacked out — people told her afterwards she had been funny and she had no memory of what she said or did, because she got so overwhelmed she no longer knew what was happening. She said she felt beloved, and that it was a beautiful thing. Her humour was intact: she told the room they were shaming her with her disability by standing up, and then added that the audience had stood for everybody.
She appeared alongside a friend who has lived with MS for far longer than she has, and the two of them, at different stages of the same disease, support each other.
Nothing here is medical advice.
In their own words
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Key moments
Saying it plainly
Her first long interview about it
She said she lives kind of in hell, and that being out at all is hard on her system.
The Emmys
Before the interview
A standing ovation she says she blacked out through. She felt beloved, and deflected it with a joke.
Not alone in it
Now
She is supported by a friend who has lived with MS for far longer, at a different stage of the same disease.
What this story is about
Where this came from
Every story here is built only from what the person said publicly themselves. These are the sources we used.
Christina Applegate is not affiliated with and has not endorsed UnTouchable.
Published 20 September 2026. Something wrong here? Ask us to correct or remove this story.